How do you administer Nplate?
Administer Nplate as a weekly subcutaneous injection with dose adjustments based upon the platelet count response. The prescribed Nplate dose may consist of a very small volume (e.g., 0.15 mL). Administer Nplate only with a syringe that contains 0.01 mL graduations.
How is Nplate stored?
Reconstituted Nplate can be kept at room temperature (25°C/77°F) or refrigerated at 2° to 8°C (36° to 46°F) for up to 24 hours prior to administration. Protect the reconstituted product from light.
What is a Nplate injection?
Nplate® is a treatment for low platelet counts in adults and children with immune thrombocytopenia (ITP) when other treatments or medicines have not worked well enough.
How do you give romiplostim injection?
Romiplostim injection comes as a powder to be mixed with liquid to be injected subcutaneously (under the skin) by a doctor or nurse in a medical office. It is usually injected once a week. Your doctor will probably start you on a low dose of romiplostim injection and adjust your dose, not more than once every week.
Where do you inject Nplate?
Nplate is administered once a week as an injection under the skin (subcutaneous). Your initial dose is 1 microgram of Nplate per kilogram of your body weight once a week.
Can Nplate be self administered?
You will prepare and self- administer Nplate® at home. Be sure to let your healthcare professional know if you had any problems, if you were able to administer the right dose, if you had any problems or have any concerns.
Is Nplate a hazardous drug?
Dosage contents may pose a health hazard only if significant absorption occurs (e.g., inhalation after major spill or leak). Avoid inhalation, skin contact, eye contact and accidental ingestion.
How often is Nplate given?
The typical dosage of Nplate for ITP is one injection given each week. For your first injection, the usual dose of Nplate for adults is 1 mcg of drug per kilogram (kg) of body weight.
Where is Nplate injected?
Nplate is injected under the skin, usually once per week. A healthcare provider will give you this injection. It may take up to 4 weeks of before Nplate is completely effective in preventing bleeding episodes. Keep receiving the medication as directed.
What is romiplostim subcutaneous for?
Romiplostim injection is used to treat low blood platelet counts (thrombocytopenia) and help prevent bleeding in patients with a blood disorder called immune thrombocytopenia (ITP).
How quickly does Nplate Work?
You’re unlikely to notice this, but certain blood tests will show that your platelet count has gone up. In a clinical study, 50% of people taking Nplate reached an average platelet count of 50,000/mcL within 2 to 3 weeks of starting treatment.
How long does it take for Nplate to work?
It may take up to 4 weeks of before Nplate is completely effective in preventing bleeding episodes. Keep receiving the medication as directed. Talk with your doctor if you have any bruising or bleeding episodes after 4 weeks of treatment.
How do you give a subcutaneous injection to a mouse?
Subcutaneous Injection in the Mouse Restrain the mouse by pulling back gently on the mouse’s tail using your dominant hand, then using the forefinger and thumb of your non-dominant hand to tent up the loose skin over the shoulders.
How is Nplate administered for the treatment of platelet disorders?
Use the lowest dose of Nplate to achieve and maintain a platelet count ≥ 50 x 109/L as necessary to reduce the risk for bleeding. Administer Nplate as a weekly subcutaneous injection with dose adjustments based upon the platelet count response. The prescribed Nplate dose may consist of a very small volume (eg, 0.15 mL).
Can Nplate be used for thrombocytopenia due to myelodysplastic syndrome?
Nplate is not indicated for the treatment of thrombocytopenia due to myelodysplastic syndrome (MDS) or any cause of thrombocytopenia other than ITP [see Warnings and Precautions (5.1)]. Nplate should be used only in patients with ITP whose degree of thrombocytopenia and clinical condition increases the risk for bleeding.