What are the classes of antiplatelet drugs?
Classes of antiplatelet drugs include:
- Irreversible cyclooxygenase inhibitors. Aspirin.
- Adenosine diphosphate (ADP) receptor inhibitors.
- Phosphodiesterase inhibitors.
- Protease-activated receptor-1 (PAR-1) antagonists.
- Glycoprotein IIB/IIIA inhibitors (intravenous use only)
- Adenosine reuptake inhibitors.
- Thromboxane inhibitors.
What is the main antiplatelet drug used in cardiac emergency medicine?
For heart disease primary and secondary prevention, daily aspirin is generally the first choice for antiplatelet therapy. Clopidogrel is prescribed instead of aspirin for people who are aspirin allergic or who cannot tolerate aspirin.
What are the most common antiplatelet drugs?
Common antiplatelets include:
- clopidogrel (Plavix)
- ticagrelor (Brilinta)
- prasugrel (Effient)
- dipyridamole.
- dipyridamole/aspirin (Aggrenox)
- ticlopidine (Ticlid)
- eptifibatide (Integrilin)
Why are Antiplatelets used for acute coronary syndrome?
Dual antiplatelet therapy reduces rates of cardiovascular events in patients with acute coronary syndrome. Specific combinations and duration of dual antiplatelet therapy should be based on patient characteristics—risk of bleeding, myocardial ischemia.
How many antiplatelet drugs are there?
Antiplatelet agents can be divided into three major types: glycoprotein platelet inhibitors (eg, abciximab, eptifibatide, tirofiban) platelet aggregation inhibitors (eg, aspirin, cangrelor, cilostazol, clopidogrel, dipyridamole, prasugrel, ticlopidine, ticagrelor)
Which drug is used in preventing platelet coagulation?
Anticoagulants, such as heparin or warfarin (also called Coumadin), slow down your body’s process of making clots. Antiplatelets, such as aspirin and clopidogrel, prevent blood cells called platelets from clumping together to form a clot. Antiplatelets are mainly taken by people who have had a heart attack or stroke.
What is the most effective antiplatelet drug?
Clopidogrel (75 mg daily) is the preferred antiplatelet.
What is ACS aspirin for?
In acute coronary syndrome, thrombotic stroke, and Kawasaki’s disease, acute use of aspirin can decrease mortality and recurrence of cardiovascular events. As secondary prevention, aspirin is believed to be effective in acute coronary syndrome, stable angina, revascularization, stroke, TIA, and atrial fibrillation.
What are the different types of anticoagulants?
Types of anticoagulants
- rivaroxaban (Xarelto)
- dabigatran (Pradaxa)
- apixaban (Eliquis)
- edoxaban (Lixiana)
What are anticoagulants & types of anticoagulants?
Anticoagulants work by interrupting the process involved in the formation of blood clots. They’re sometimes called “blood-thinning” medicines, although they don’t actually make the blood thinner….Types of anticoagulants
- rivaroxaban (Xarelto)
- dabigatran (Pradaxa)
- apixaban (Eliquis)
- edoxaban (Lixiana)
Why is clopidogrel and aspirin used together?
Both these antiplatelet agents have a potent protective effect against adverse vascular events, but the combination of these two agents has an even stronger antiplatelet effect translating into superior antithrombotic protection in coronary, cerebral or peripheral arterial disease, without an inordinate increase in …
What classification is Plavix?
Clopidogrel is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.
Is clopidogrel an anticoagulant or antiplatelet?
Clopidogrel is an antiplatelet medicine. It prevents platelets (a type of blood cell) from sticking together and forming a dangerous blood clot.
What are the contraindications of clopidogrel?
Contraindications / Precautions
- General Information.
- Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma.
- Hepatic disease.
- Renal disease, renal failure, renal impairment.
- Poor metabolizers.
- Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia.
- Breast-feeding.
- Geriatric.