What is UniProt in biology?
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
What is the use of UniProt?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
What is Symporter and Antiporter?
Symporters and antiporters are involved in active transport. Antiporters transport molecules in opposite directions, while symporters transport molecules in the same direction.
Is UniProt and swissprot same?
Swiss-Prot (created in 1986) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. UniProtKB/Swiss-Prot is now the reviewed section of the UniProt Knowledgebase.
How many sequences are in UniProt?
INTRODUCTION Release 2022_02 of 25-May-2022 of UniProtKB/TrEMBL contains 231354261 sequence entries, comprising 81115895851 amino acids.
What is UniProt Knowledgebase?
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.
What is symport transport?
A symporter is an integral membrane protein that is involved in the transport of two different molecules across the cell membrane in the same direction. The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of cotransporter.
What is symport short answer?
Symport is the type of transport in which two different molecules can move through a membrane in same direction by using a common carrier mechanism. The transporter is called a symporter which is an integral protein and it works in the cell membrane the molecules to transport across the membrane at the same time.
What is UniProt in bioinformatics Slideshare?
1. UniProt The Universal Protein Resource (UniProt) is a unreservedly open database of protein sequence and useful information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
What is UniRef90?
UniRef90 is built by clustering UniRef100 sequences such that each cluster is composed of sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence in the cluster (the seed sequence).
What is difference between symport and antiport?
Symport: Movement of two molecules in the same direction through a protein channel is known as symport. Antiport: Movement of two molecules in the opposite direction through a protein channel is known as antiport.
How many sequences does UniProt contain?
UniProtKB/Swiss-Prot contains over 550 000 sequences that have been created by our expert biocuration team. For these entries experimental information has been extracted from the literature and organized and summarized, greatly easing scientists access to protein information.
What data and tools does UniProt provide?
To build upon this protein data and to aid analysis, UniProt provides three main tools; ‘BLAST’ (Basic Local Alignment Search Tool), ‘Align’ multiple sequence alignment tool and ‘Retrieve/ID Mapping’ for batch retrievals of UniProt entries and ID mapping between UniProt and external databases.
What is UniParc in UniProt?
The UniProt Archive (UniParc) is a comprehensive and non-redundant database that contains most of the publicly available protein sequences in the world. Proteins may exist in different source databases and in multiple copies in the same database.
What is antiport transport?
Antiport is a form of active transport. Two species of solutes or ions are pumped in opposite directions across a membrane in antiport. One of these two species is permitted to flow from high concentration to low.
What is TrEMBL?
Introduction TrEMBL is a computer-annotated protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TrEMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT.